Torso Healthcare manufactures Cefepime 1000mg & Tazobactum 125mg Injection as a dry powder for injection and supplies it to hospitals, distributors and franchise partners who want the vial carrying their own brand. One vial holds 1000 mg of cefepime with 125 mg of tazobactam, which adds up to the 1.125 g strength most Indian hospitals mean when they order cefepime with an inhibitor.

What is Cefepime 1000mg & Tazobactum 125mg Injection?

Cefepime 1000mg & Tazobactum 125mg Injection is a fixed dose antibiotic combination holding 1000 mg of cefepime and 125 mg of tazobactam in one vial, given into a vein to treat moderate to severe bacterial infections in hospital patients. Cefepime is a semi synthetic broad spectrum cephalosporin that kills bacteria by stopping them from building a cell wall. Tazobactam is a penicillanic acid sulfone that blocks beta lactamase, the enzyme that resistant bacteria use to break the cephalosporin apart.

Approved labeling spells the inhibitor tazobactam, while Indian catalogs, tender lists, and brand names often write it as tazobactum. Both spellings point to the same molecule, and the same inhibitor sits inside ceftazidime tazobactam combination packs as well.

The 8 to 1 Ratio Behind the 1.125 g Pack

Divide 1000 mg of cefepime by 125 mg of tazobactam and the answer is 8 to 1. That ratio is not a coincidence. Piperacillin with tazobactam has used the same 8 to 1 split for years, with 4 g of piperacillin alongside 500 mg of tazobactam, and the 1.125 g cefepime pack follows that established convention.

A heavier 1.5 g version also sells in India, carrying 500 mg of tazobactam behind the same gram of cefepime. More inhibitors do not automatically mean a better antibiotic, because the inhibitor protects the cephalosporin rather than killing bacteria itself. Which pack a hospital buys usually follows what its prescribers are used to and what the tender asks for.

Cefepime 1000mg & Tazobactum 125mg Injection Uses

Labeling for this combination covers moderate to severe infections caused by, or suspected to be caused by, susceptible beta lactamase producing bacteria, where cefepime on its own would not be enough. It belongs with the rest of our critical care range. Listed uses include:

• Complicated and uncomplicated urinary tract infections
• Uncomplicated skin and skin structure infections
• Complicated intra abdominal infections
• Moderate to severe infections where beta lactamase producing organisms are involved

A hypothetical example, written as an illustration and not as a case report: a patient develops an infected surgical wound that an earlier cephalosporin fails to clear, and the culture reports a beta lactamase producing organism. Cefepime with tazobactam is one of the options that labeling supports in that situation, because the inhibitor keeps the enzyme occupied while the cephalosporin does the work.

Reconstitution and Handling Notes

Keep vials below 30 degrees C and protected from light until a trained member of staff prepares the dose. Two timings from labeling are worth passing to the ward rather than leaving in the insert.

For the intravenous route, the powder is reconstituted with 10 mL of sterile water for injection and infused over about 30 minutes, and the prepared solution holds for roughly 24 hours at 20 to 25 degrees C. The intramuscular route uses 2.4 mL of sterile water for injection, and that solution holds for only about one hour at room temperature. That short window is the detail most listings leave out, and it decides whether a dose gets prepared at the bedside or sent back.

Cefepime 1000mg & Tazobactum 125mg Injection Side Effects

Reported effects are usually transient and mild to moderate, and they track what cefepime alone produces. Labeling puts rash at about 4 percent, diarrhea at 3 percent, nausea at 2 percent, and vomiting, itching, fever and headache at roughly 1 percent each. Laboratory changes are more common than symptoms, with a positive Coombs test without hemolysis in about 16 percent, and smaller shifts in phosphorus and liver enzymes.

Blood counts deserve a mention of their own. Leukopenia, neutropenia, agranulocytosis and thrombocytopenia have all been reported, which is why a longer course usually comes with monitoring. Labeling also carries reports of encephalopathy, myoclonus and seizures, mostly in patients with reduced kidney function who received more than the recommended schedule, though some occurred even after the dose was adjusted.

The combination is contraindicated in anyone hypersensitive to cefepime or other cephalosporins, and it is avoided in patients with a previous immediate reaction to penicillins. Kidney function needs watching when it runs alongside a high dose of aminoglycoside or a strong diuretic such as furosemide, and doctors reduce the dose when kidney function falls.

Cefepime 1000mg & Tazobactum 125mg Injection Price

We only take bulk orders and price each one on quantity, so the rate per vial drops as the order grows. Tell us the quantity, the pack you need, and the market you supply, and the team comes back with current rates. PCD pharma franchise partners holding a single territory are quoted on the same footing.

Brands and Own Label Supply

The 1.125 g pack sells in India under names such as Cefpime-TZ, I-Pime TZ, and Tozic, most of them built by adding a TZ tag to a parent cefepime brand. Through third-party manufacturing, the same vial reaches the market under your brand name, carton, and artwork instead of an established label, and the brand equity you build stays with you. Our own brand name is TOSOCEF TZ 1.125 Injection.

Cefepime 1000mg & Tazobactum 125mg Injection Manufacturer in India

Torso Healthcare is a WHO GMP certified manufacturer of injectables in India, and cefepime injection manufacturers sit within the beta lactam range we already run. Buyers stocking this vial usually carry the wider cephalosporin line too, including cefoperazone 1gm injection, which keeps purchasing with one supplier rather than several.

A certificate of analysis travels with every batch, pack, and carton. Options are built around your brand, and dispatch runs across India and export markets. Hospital supply firms, distributors, and new ventures use the same route to add an injectable line without running a plant.

Frequently Asked Questions

How much tazobactam is in the 1.125 g vial?

The vial holds 125 mg of tazobactam alongside 1000 mg of cefepime, which together make the 1.125 g strength. That works out to an 8 to 1 ratio of antibiotic to inhibitor, the same split used in piperacillin and tazobactam products.

Why do some packs spell the inhibitor as tazobactum?

Tazobactam is the spelling used in approved labeling. Tazobactum is a variant that became common in Indian product catalogs, tender documents, and brand names. The molecule is identical, so a pack labeled either way contains the same inhibitor.

Can cefepime with tazobactam be given as an intramuscular injection?

Yes, labeling allows deep intramuscular injection where that route suits the patient, though the intravenous infusion is the usual choice. The route is decided by the treating doctor, and trained staff prepare the dose in either case.

How long does the reconstituted solution stay usable?

An intravenous solution prepared with sterile water for injection holds for about 24 hours at 20 to 25 degrees C. An intramuscular solution holds for only about one hour at room temperature, so it needs to be prepared close to the time of the injection.

Do you supply this pack for third-party and PCD orders?

Yes. The 1.125 g vial is available for third-party manufacturing and PCD franchise supply, with your own brand name and artwork on the carton. Batch documentation, including a certificate of analysis, goes out with each consignment.

For Cefepime 1000mg & Tazobactum 125mg Injection in bulk or under your own label, share your requirement with the pack size and quantity, and Torso Healthcare will come back with current rates.

Composition, indications, storage, and safety details on this page follow approved product labeling for cefepime and tazobactam, including the approved cefepime labeling.

Disclaimer: This page is written for pharmaceutical businesses and healthcare professionals as reference information only. It is not medical advice, and it does not replace guidance from a qualified doctor. Cefepime and tazobactam injection is a prescription medicine and must be used only under medical supervision.