Cefepime & tazobactam for injection 1.5gm puts a broad spectrum cephalosporin and a beta lactamase inhibitor in the same vial, 1000 mg of cefepime with 500 mg of tazobactam. Hospitals turn to it when the organism behind an infection produces the enzymes that would otherwise break cefepime down before it works. Torso Healthcare makes the pack as a sterile powder for injection and supplies distributors, hospitals and franchise partners who want it carrying their own label.

What is cefepime & tazobactam for injection 1.5gm?

Cefepime & tazobactam for injection 1.5gm is a fixed-dose antibiotic combination holding 1000 mg of cefepime and 500 mg of tazobactam in a single vial, given as an intravenous infusion to treat moderate to severe bacterial infections in hospital patients. Cefepime is a semi synthetic cephalosporin that kills bacteria by stopping them from building a working cell wall. Tazobactam is a penicillanic acid sulfone, and its only real job is blocking beta lactamase.

The combination is an Indian market formulation, so most listings for it come from Indian suppliers rather than global drug references. Cefepime on its own is the internationally registered product, and we make it alongside the rest of our cephalosporin injections range.

Why Cefepime Is Paired With Tazobactam

Cefepime already covers a wide span of gram positive and gram negative organisms, and it holds useful activity against Pseudomonas aeruginosa. That is why hospitals keep it for serious infections rather than routine ones. What cefepime cannot do on its own is survive bacteria that pump out beta lactamase.

Tazobactam closes that gap. It kills very little by itself, so it adds no spectrum of its own, but it occupies the enzymes long enough for cefepime to reach the cell wall. Approved labeling positions the pair for infections caused by beta lactamase producing bacteria where cefepime alone would fall short. The same reasoning sits behind ceftazidime with tazobactam in our catalog.

Cefepime & Tazobactam For Injection 1.5gm Uses

Labeling for this combination lists moderate to severe infections caused by, or suspected to be caused by, susceptible beta lactamase producing bacteria. Named indications include:

• Complicated and uncomplicated urinary tract infections
• Uncomplicated skin and skin structure infections
• Complicated intra abdominal infections
• Moderate to severe infections where cefepime alone would not be effective

A hypothetical ward example, written as an illustration rather than a case report: a patient with a complicated urinary tract infection stops responding to an earlier cephalosporin, and the lab reports a beta lactamase producing organism. The team moves to cefepime with tazobactam so the inhibitor can keep those enzymes occupied while the cephalosporin clears the infection.

Cefepime & Tazobactam For Injection 1.5gm Side Effects

Reported effects are usually transient and mild to moderate, and they match what cefepime alone produces. Rates published in product labeling include rash in about 4 percent of patients, diarrhea in 3 percent, nausea in 2 percent, and vomiting, itching, fever and headache in about 1 percent each. A positive Coombs test without hemolysis shows up far more often, in roughly 16 percent, which matters when a lab result needs reading rather than treating.

One warning deserves more weight than the rest, and most product listings skip it. Encephalopathy, myoclonus and seizures have been reported with cefepime. Most cases involved patients with reduced kidney function who received more than the recommended schedule, and some occurred even where the dose had already been adjusted for kidney function. Doctors lower the dose when kidney function drops and watch for confusion or twitching during treatment.

Other cautions carried in labeling include anaphylaxis, low white cell and platelet counts, and serious skin reactions. The combination is contraindicated in anyone hypersensitive to cephalosporins, and it needs care in patients with a history of penicillin allergy. Kidney function needs monitoring when it runs alongside high dose aminoglycosides or a strong diuretic such as furosemide.

Pack Strengths, Storage, and Reconstitution

The cefepime content stays the same across the two common packs. What changes is how much tazobactam sits behind it.

Store vials below 30 degrees C, protected from light, and keep them dry until use. Trained hospital staff reconstitute the powder with sterile water for injection and give it as an infusion over roughly half an hour, or by deep intramuscular injection where that route is indicated. A reconstituted intravenous solution holds for about 24 hours at 20 to 25 degrees C, which is worth knowing when you plan ward stock rather than central pharmacy stock.

Cefepime & Tazobactam For Injection 1.5gm Price

Torso Healthcare only takes bulk orders and prices each order on quantity, so the rate per vial falls as the order grows. Send the pack size, the quantity, and the market you supply, and you get current rates for that order instead of a shelf price. PCD franchise partners working a single territory are quoted the same way.

Cefepime Tazobactam Brands

Indian brands of this combination usually carry a TZ or XP tag on the parent cefepime name, with Epicef-TZ, Celrim TZ and Cepime-TZ among the ones buyers meet most often. Through third party manufacturing, you sell the same 1.5 gm pack under your own brand name, carton and artwork rather than paying a premium for an existing label. Owning the brand is usually what protects the margin as a company grows. The name of our brand is RSOCEF TZ 1.5 Injection.

Cefepime & Tazobactam For Injection 1.5gm Manufacturer in India

Torso Healthcare is a WHO GMP-certified manufacturer of injectables in India, and cefepime injection manufacturing sits within the beta lactam range we already run. Buyers who stock this pack usually stock the wider cephalosporin and carbapenem lines too, which keeps ordering with a single supplier.

Partners get consistent batch quality, a certificate of analysis with every batch, custom pack and carton options, and steady dispatch across India and export markets. That suits hospital supply firms, distributors, and anyone building a line of antibiotic products without running a plant of their own.

Frequently Asked Questions

Is cefepime and tazobactam the same as piperacillin and tazobactam?

No. The inhibitor is the same in both, but the antibiotic is not. Cefepime is a cephalosporin and piperacillin is a penicillin, so the two combinations cover different organisms and suit different infections. A culture and sensitivity report decides which one fits a patient.

Why does cefepime need tazobactam added to it?

Many gram negative bacteria release beta lactamase, an enzyme that breaks cefepime down before it can act. Tazobactam blocks that enzyme. It adds almost no killing power of its own, so the benefit is purely in protecting the cefepime already in the vial.

What is the difference between the 1.125 gm and 1.5 gm packs?

Both hold 1000 mg of cefepime. The 1.125 gm pack adds 125 mg of tazobactam and the 1.5 gm pack adds 500 mg, so the larger pack carries four times the inhibitor behind the same amount of antibiotic. Buyers choose based on what their hospitals prescribe.

Can I market this injection under my own brand?

Yes. Torso Healthcare supplies the 1.5 gm pack through third-party manufacturing and PCD franchise arrangements, so the carton, brand name, and artwork are yours. Supporting documentation travels with the order, including a certificate of analysis for each batch.

How is the per-vial rate decided for a bulk order?

Quantity drives it, along with pack configuration and the destination market. Larger orders bring the per-vial rate down. Share those details, and the team replies with a quote at current rates, since orders are priced individually rather than sold at a listed price.

Torso Healthcare supplies Cefepime & tazobactam for injection 1.5gm to distributors, hospitals, and franchise partners across India and export markets. Send your pack size and quantity to get a quote with current rates.

Composition, indications, storage, and safety details on this page follow approved product labeling for cefepime and tazobactam, including the FDA cefepime label.

Disclaimer: This page is written for pharmaceutical businesses and healthcare professionals as reference information only. It is not medical advice, and it does not replace guidance from a qualified doctor. Cefepime and tazobactam injection is a prescription medicine and must be used only under medical supervision.