Cefepime 1 gm is the vial most adult antibiotic courses in a hospital are built around, which is why it turns over faster than the 500 mg or 2 g sizes. It is a broad-spectrum cephalosporin given intravenously for serious infections, including pneumonia and fever in patients with low white cell counts. Torso Healthcare manufactures the 1 g vial as a sterile powder for injection and supplies hospitals, distributors, and franchise partners who want it under their own label.

Inj Cefepime 1 gm Composition

Each vial holds cefepime hydrochloride equivalent to 1000 mg of cefepime, which is why some catalogs list it as cefepime 1000mg injection. Labeling states the strength as the cefepime it delivers, not the weight of the salt, so a 1 g vial gives a full gram of active drug. The vial also carries L-arginine, roughly 707 mg per gram of cefepime, which is there to bring the reconstituted solution to a pH between 4 and 6 rather than to treat anything.

That buffer is the part most product listings leave out, and it matters to a buyer comparing specifications, because potency has to land between 90 and 115 percent of the labeled amount for the vial to pass.

Cefepime 1 gm Uses

Cefepime is a parenteral cephalosporin kept for infections that need something stronger than an oral course, which puts it in the same shelf as the rest of our critical care injections. Approved labeling lists these uses:

• Moderate to severe pneumonia, including cases with bacteremia
• Empiric treatment of fever in patients with low white cell counts
• Complicated and uncomplicated urinary tract infections, including pyelonephritis
• Uncomplicated skin and skin structure infections
• Complicated intra-abdominal infections are treated together with metronidazole

A hypothetical ward example, written as an illustration and not as a case report: a patient on chemotherapy spikes a fever while the white cell count is low, and no organism has been identified yet. Cefepime is one of the agents labeled to support single-drug empiric coverage in that situation, which is part of why hospitals keep the 1 g vial in stock rather than ordering it per case.

Inj Cefepime 1 gm Dose and Administration

Dosing is set by the treating doctor and depends on the infection, how severe it is, and how well the kidneys are working, so no schedule is published here. Two points from labeling matter when you handle the product rather than prescribe it.

The intravenous route is an infusion running about 30 minutes. The intramuscular route exists, but labeling limits it to mild to moderate urinary tract infections caused by E coli, where that route suits the patient better. Dose adjustment is required once creatinine clearance falls to 60 mL per minute or below, and patients on dialysis follow their own schedule.

Side Effects and Safety Warnings

Reported reactions are mostly local and mild. Labeling puts injection site reactions at about 3 percent, with phlebitis at 1.3 percent, and rash at 1.1 percent. Diarrhea, nausea, vomiting, headache, fever, and itching each come in under 1 percent. A positive Coombs test without hemolysis appears in about 16 percent, which is a laboratory finding to read correctly rather than a problem to treat.

The warning that deserves real attention is neurological. Encephalopathy, myoclonus, seizures, and nonconvulsive status epilepticus have all been reported. Most cases involved patients with reduced kidney function who did not get the dose adjusted, though some happened even with adjusted dosing. Most reactions reversed once the drug was stopped or after hemodialysis, which is why early recognition matters more than anything else.

Cefepime is contraindicated in anyone with an immediate hypersensitivity reaction to cephalosporins, penicillins, or other beta-lactams, and cross-reactivity has been documented in up to 10 percent of patients with a penicillin allergy history. Antibiotic-associated diarrhea linked to Clostridioides difficile can appear during treatment or more than two months after it ends.

Which Vial Size to Stock

Cefepime is supplied in three vial sizes, and choosing between them is a stocking decision rather than a clinical one. The cefepime 1g vial sits in the middle and carries most of the volume. The table below is how most hospital buyers think about it.

Inj Cefepime 1 gm Brand Name Options

Cefepime sells in India under many brand names, since the molecule has been off patent for years, and most large companies carry a version. Rather than competing against an established label on price, third-party pharma manufacturing lets you put the same cefepime 1gm injection on the market under your own brand name, carton, and artwork. The brand stays yours, which is usually what protects the margin as volumes grow. Our brand name is TOROCEF-1 Injection.

Cefepime Injection 1gm Price

The cefepime injection 1gm price is MRP ₹443 per vial. Vial size is what moves it, because the 1 g and 2 g presentations do not cost the same to fill, and the inj cefepime 1 gm price per unit falls as the pack count rises.

Beta-lactam production carries the rest, since cephalosporins run in segregated areas with their own cleaning validation. That segregation is a regulatory requirement rather than a choice, which is why beta-lactam quotes do not track general injectable rates. Batch pricing then depends on the number of vials ordered. Send your monthly requirement for cefepime 1 gm injection, with the vial sizes and the destination market, and the team will come back with current rates.

Cefepime 1 gm Injection Manufacturer in India

Torso Healthcare is a WHO GMP-certified manufacturer of injectables in India, and cefepime manufacturing in India sits inside the beta-lactam range we already run. Buyers who stock this vial usually carry the wider cephalosporin line too, including cefoperazone injection, which keeps ordering with one supplier instead of three.

Every batch ships with a certificate of analysis, and pack and carton options are built to your brand. Hospital supply firms, distributors, and new pharma ventures use the same route to add carbapenems such as meropenem 1 gm vial without running a plant of their own.

Frequently Asked Questions

What does an inj cefepime 1 gm vial contain?

It contains cefepime hydrochloride equivalent to 1000 mg of cefepime, plus L-arginine as a buffer at roughly 707 mg per gram of cefepime. The strength of the label is the amount of cefepime delivered, not the weight of the hydrochloride salt.

Is cefepime a fourth-generation cephalosporin?

Clinicians usually group it as fourth generation, because it covers a wider span of gram-negative organisms than earlier cephalosporins. Approved labeling itself does not assign a generation and simply describes cefepime as a semi-synthetic broad-spectrum cephalosporin for parenteral use.

Can cefepime 1 gm be given as an intramuscular injection?

Yes, but labeling limits that route. Intramuscular use is reserved for mild to moderate urinary tract infections caused by E coli, where that route suits the patient. The usual route is an intravenous infusion running for about half an hour.

Does cefepime need a dose change in kidney problems?

Yes. Labeling requires dose adjustment once creatinine clearance reaches 60 mL per minute or below, and dialysis patients follow a separate schedule. Skipping that adjustment is the single most common factor in the serious neurological reactions reported with this drug.

Can I sell cefepime 1 gm injection under my own brand name?

Yes. Torso Healthcare supplies the 1 g vial through third-party manufacturing and PCD franchise arrangements, so the brand name, carton, and artwork belong to you. Batch documentation, including a certificate of analysis, travels with each order.

Torso Healthcare supplies cefepime 1 gm injection to hospitals, distributors, and franchise partners across India and export markets. Send your quantity and pack requirement to get current rates for your order.

Composition, indications, storage, and safety details on this page follow the approved FDA cefepime label.

Disclaimer: This page is written for pharmaceutical businesses and healthcare professionals as reference information only. It is not medical advice, and it does not replace guidance from a qualified doctor. Cefepime injection is a prescription medicine and must be used only under medical supervision.