Anyone comparing lactulose syrup manufacturers in India runs into the same three puzzles. The strength is written two different ways on two different labels. Retail prices for the same molecule swing by about three times. And almost nobody explains that lactulose sells into two very different markets, which is what should decide your pack sizes.
This article sorts all three out, with current brand prices, the manufacturers active in India, and what to check before you place an order.
The short version: lactulose is one molecule, two markets, and a wide price band. Pick your supplier around pack size and documentation, not the headline rate.
What is lactulose syrup used for?
Lactulose is an osmotic laxative, and the approved product information clears it for two distinct uses. The first is constipation, which is the retail and pharmacy market. The second is hepatic encephalopathy, meaning the treatment and prevention of hepatic coma or precoma in liver disease, which is a hospital market and is approved for adults.
That split matters commercially more than it looks. A constipation buyer wants small retail bottles moving through chemists. A liver unit wants large bottles, consistent supply, and documentation, because the product is used daily and at higher volumes. Deciding which market you are selling into answers most of your packaging questions before you ever talk to a factory.
Lactulose serves a retail constipation market and a hospital liver market, and the two want different pack sizes.
Why do labels show 10 g per 15 ml and 3.335 g per 5 ml?
Because they are the same thing. Divide either one out and you get roughly 0.667 g of lactulose per milliliter. Indian labels tend to print 10 g per 15 ml, while the European style is 3.335 g per 5 ml, and both describe a solution of about 66.7 percent weight by volume.
This trips up new buyers who think they are comparing a stronger product with a weaker one. They are not. When you compare quotes, convert everything to a per-milliliter or per-100 ml basis first; otherwise, the numbers are not comparable at all.
The two strength formats describe one concentration, about 0.667 g per mL. Always normalize before comparing.
What does lactulose solution cost in India?
Anyone researching lactulose solution price in India finds numbers that look wildly inconsistent, because the packs are different sizes. Normalized to 100 ml, the picture is much clearer. Current retail listings put the branded products in a fairly tight band and the unbranded generics far below it.
| Brand | Marketer | Pack and MRP | Per 100 ml |
| Duphalac | Abbott India | 250 ml, ₹322.87 | About ₹129 |
| Livoluk | Mankind Pharmaceuticals | 100 ml, ₹129.53 | About ₹130 |
| Looz | Intas Pharmaceuticals | 360 ml, ₹375.66 | About ₹104 |
| Lactulose Syrup | Adcock Ingram Healthcare | 100 ml, ₹47.30 | About ₹47 |
So the branded shelf sits around ₹104 to ₹130 per 100 ml, and an unbranded generic lands near ₹47. That is close to a threefold gap for the same molecule at the same concentration, and it is exactly the room a new brand can price into. Figures are MRP as listed in November 2026, and retail prices move, so treat them as a benchmark rather than a quote.
Normalized to 100 ml, branded lactulose runs about ₹104 to ₹130 and unbranded generics about ₹47.
Top Lactulose Syrup Manufacturers in India
These are companies active in lactulose supply in India as of 2026, covering brand owners, bulk suppliers, and contract manufacturers. Torso Healthcare is listed first as the featured third-party partner; the rest appear by general presence rather than a ranking.
| # | Company | What they supply | Notes |
| 1 | Torso Healthcare | Syrup third-party and PCD supply | |
| 2 | Abbott India | Finished brand | Markets Duphalac, the reference brand |
| 3 | Mankind Pharmaceuticals | Finished brand | Markets Livoluk across 60 ml to 450 ml packs |
| 4 | Intas Pharmaceuticals | Finished brand | Markets Looz, including a 360 ml pack |
| 5 | Adcock Ingram Healthcare | Generic finished supply | Markets unbranded lactulose syrup |
| 6 | Lactose India Limited | Bulk lactulose | Lists lactulose among its product range |
| 7 | Macro Labs | Finished brand | Markets Gutloose lactulose solution |
| 8 | Strauss Wellness | Finished and contract supply | Lists lactulose solution in its range |
| 9 | Chemcopia | Bulk and contract supply | Lists lactulose manufacturing |
A list like this is where the work starts, not where it ends. The useful step is asking each name for a drug license number, a batch Certificate of Analysis, and a written per-bottle quote. The same applies when you evaluate syrup production partners for any other liquid product.
Treat any manufacturer list as a shortlist, then let license numbers and written quotes decide.
Which pack sizes should you order?
Lactulose syrup manufacturers in India quote a wider pack range than most liquids, from 60 ml up to 450 ml. The range exists because the two markets consume it so differently.
- 60 ml and 100 ml: trial packs and short constipation courses, the easiest retail entry point.
- 150 ml and 200 ml: the mainstream chemist sizes, and usually the best balance of margin and turnover.
- 250 ml to 450 ml: longer therapy and hospital use, including liver patients who take it daily.
A bigger bottle changes more than the volume. It shifts the filling line setup, the closure, the carton, and the freight cost per unit, so quote each size separately. Any partner running a serious liquid oral manufacturing line will price them that way without being asked.
Start with 100 ml and 200 ml for retail, and add a 450 ml pack only if you are selling into hospitals.
How do you choose a syrup manufacturing partner?
When you compare lactulose syrup manufacturers in India, let the liquid itself shape the checklist. Lactulose is thick and sugary, which makes it harder to handle than a thin syrup.
- A dedicated liquid oral block with the right mixing and filling equipment, not a tablet plant that occasionally fills bottles.
- A valid manufacturing license for oral liquids, and WHO-GMP if you intend to export.
- Stability data for your pack, because syrups behave differently in glass and in PET across Indian summers.
- A Certificate of Analysis from a recent batch, showing assay against the label claim.
- Clarity on bottle, cap, and measuring cup supply, which is where liquid orders usually slip on timelines.
Location is worth a thought too. A large share of Indian liquid oral capacity sits in the Himachal belt, and buyers often shortlist Baddi syrup units for that reason. On the input side, lactulose is well supplied: public regulatory databases list 35 API suppliers for the molecule, with 22 US DMFs and 14 CEP certificates on file, so raw material access is rarely the constraint.
Check for a real liquid oral line, stability data for your exact pack, and confirmed bottle and cap supply.
How to Launch Your Own Lactulose Syrup Brand
The order below saves the most rework, mainly because packaging decisions lock in early and are expensive to reverse.
- Decide your market first, retail constipation or hospital supply, because it sets your pack sizes and your pricing.
- Fix the pack range, typically 100 ml and 200 ml to start, and ask for a separate quote per size.
- Verify the manufacturer’s license for oral liquids and ask for a recent Certificate of Analysis.
- Request samples and check taste, viscosity, and pourability. Lactulose is taken daily, so palatability drives repeat sales.
- Agree on the commercial route. A contract production arrangement keeps the brand yours, and the plant produces to your order.
- Approve artwork against labeling rules, confirm the batch, and collect the batch test report with the delivery.
If you would rather sell ready products in a protected territory than own a formulation, a franchise supply model gets you to market faster, though the brand is not yours to keep.
Decide the market before the pack, and taste the sample before you commit to a batch.
Frequently Asked Questions
What is lactulose syrup used for?
Lactulose is an osmotic laxative used to treat constipation, and it is also approved to treat and prevent hepatic encephalopathy, a brain complication of liver disease. The liver indication is approved for adults.
Is 10 g per 15 ml stronger than 3.335 g per 5 ml?
No, they are identical. Both work out to about 0.667 g of lactulose per milliliter, or roughly a 66.7 percent weight-by-volume solution. The two formats are just different labeling conventions.
How much does lactulose solution cost in India?
Branded solutions run about ₹104 to ₹130 per 100 ml, and unbranded generics about ₹47 per 100 ml, based on listed MRP in November 2026. Because packs range from 60 ml to 450 ml, always convert to a per 100 ml figure before comparing.
Can lactulose be taken during pregnancy?
The approved product information states that lactulose can be used during pregnancy when a physician considers it necessary, because systemic absorption is negligible. That decision belongs to the treating doctor, not to a label comparison.
What is the minimum order for third-party lactulose syrup manufacturing?
Minimums vary by manufacturer and by pack size, and liquid orders are usually quoted in bottles per batch rather than in liters. Ask for the minimum against each pack size you want, because a 450 ml run and a 100 ml run rarely carry the same minimum.
Do I need my own license to sell a lactulose brand?
Yes. Lactulose is a drug product, so the brand owner needs the appropriate drug license to market it, separate from the manufacturing license held by the factory. Confirm the exact category with your state drug authority before printing labels.
Making the Decision
Shortlisting lactulose syrup manufacturers in India gets straightforward once you normalize the strengths, convert every quote to a per 100 ml basis, and decide whether you are selling to chemists or to hospitals. Ask for the license, the Certificate of Analysis, and a sample before anything else. For a quote on lactulose syrup or a wider liquid orals range, send your pack sizes and quantities to Torso Healthcare.
Disclaimer: This article is for general business information only. It is not medical advice. Lactulose should be used only as directed by a qualified doctor. Prices, pack availability, company details, and regulatory requirements vary and change over time, so verify current details before relying on them.
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