Meropenem sulbactam 1.5 gm injection is a broad-spectrum carbapenem antibiotic combination used in hospitals to treat serious and drug-resistant bacterial infections. Torso Healthcare manufactures and supplies it as a sterile powder for injection, built for third-party and PCD pharma partners who want a dependable generic under their own brand.

What is meropenem sulbactam 1.5 gm injection?

Meropenem sulbactam 1.5 gm injection is a fixed-dose combination antibiotic that pairs 1000 mg of meropenem with 500 mg of sulbactam, given in hospitals to treat severe and drug-resistant bacterial infections. Meropenem is a carbapenem, one of the strongest classes of antibiotics, and is usually held back for infections that other drugs cannot clear. Sulbactam is a beta-lactamase inhibitor, and it does two useful jobs inside this pack. It shields meropenem from the enzymes that many hospital bacteria produce, and it adds direct activity against Acinetobacter, an organism behind a large share of hard-to-treat infections in critical care.

The 1.5 g label splits into 1000 mg of meropenem and 500 mg of sulbactam, a two-to-one ratio, so a buyer reading the strength knows exactly what sits inside the vial. Some brands also add disodium EDTA, an adjuvant that helps the combination hold up against certain metallo-beta-lactamase producing strains, so you will find both plain and EDTA versions on the market. The combination itself is largely an Indian-market formulation, which is why almost all product listings and prescribing demand for it come from India rather than global drug references.

How It Works

Meropenem is a beta lactam antibiotic. Once it reaches the bloodstream, it binds to the penicillin-binding proteins that bacteria use to build and repair their outer wall. With those proteins blocked, the wall gives way, the cell bursts, and the infection dies back. It works against a wide mix of gram-positive, gram-negative, and anaerobic bacteria, which is why clinicians reach for it in severe cases.

Some bacteria fight back by releasing beta-lactamase, an enzyme that breaks the antibiotic before it can act. Sulbactam blocks that enzyme. On its own, it does little against most infections, yet paired with meropenem, it keeps the carbapenem active against strains that would otherwise resist it. Against Acinetobacter, sulbactam goes further and attacks the bacterium directly, and that is the main reason this pairing exists.

Meropenem Sulbactam 1.5 gm Uses

Doctors prescribe this combination for infections that need a powerful antibiotic delivered straight into a vein. Common uses include:

• Pneumonia, including hospital-acquired and ventilator-associated cases
• Complicated urinary tract infections
• Complicated intra-abdominal infections
• Skin and soft tissue infections
• Bloodstream infections and sepsis
• Bacterial meningitis
• Fever in patients with low white blood cell counts (febrile neutropenia)

Take a common surgical-ward example. After abdominal surgery, a patient develops sepsis from a resistant gram-negative organism that first-line antibiotics fail to control. The culture report points to a strain that produces enzymes able to break down many beta lactams. The team switches to meropenem with sulbactam, because the sulbactam holds those enzymes at bay long enough for the carbapenem to clear the infection. That kind of resistant, high-stakes case is where this pack earns its place on the hospital shelf.

Meropenem Sulbactam 1.5 gm Injection Side Effects

Most patients tolerate this injection well, though some effects can show up. The common ones are:

• Nausea, vomiting, or loose stools
• Headache
• Pain, redness, or swelling at the injection site
• Skin rash or itching
• A rise in platelet count is seen on blood tests

Two points get skipped on most generic listings, and both matter in practice. First, meropenem can lower the seizure threshold, and it sharply reduces blood levels of valproic acid, so a patient already on that anti-seizure medicine can have breakthrough seizures if the two are combined. Second, broad carbapenems can trigger severe antibiotic-associated diarrhea linked to Clostridioides difficile, which needs prompt medical attention rather than a standard anti-diarrhea remedy. Doctors weigh both before and during treatment.

Meropenem Sulbactam 1.5 gm Injection Price

Price moves with brand, pack size, and order volume. As an indicative guide, the MRP for a meropenem and sulbactam 1.5 g vial in India runs roughly Rs 450 to Rs 3500 across common brands, with a few premium labels priced higher. Those are retail figures.

For distributors and PCD partners buying in volume, the supply price and PTS sit well below MRP, which is where the working margin lives. Torso Healthcare shares current per-unit pricing and slab rates on request, so you can quote from real numbers rather than a fixed retail figure.

Meropenem Sulbactam 1.5 gm Brands

The combination sells in India under several brand names, with Meroplan S, Meromac Plus, Mero SB, and Merotrol S among the more widely stocked. When you partner with Torso Healthcare for third-party manufacturing or a PCD franchise, you market the same quality product under your own brand name, packaging, and artwork, instead of paying a premium for an existing label.

That control over branding is often what decides the margin for a growing pharma business. We also have our own brand name, which is TOROMER S.

Meropenem Sulbactam 1.5 gm Manufacturer in India

Torso Healthcare is a WHO GMP and ISO certified meropenem injection manufacturer and third-party supplier of injectables in India, with production units in Baddi, Himachal Pradesh. Alongside this 1.5 g combination, we also make plain meropenem 500 mg injection and meropenem 1 g injection, plus the sibling meropenem and tazobactam injection, so you can build a full carbapenem range under one roof.

Partners get consistent batch quality, complete documentation including COA, custom pack sizes, and dependable delivery across a wide network. Our PCD pharma franchise and contract injection manufacturing services let you add this antibiotic to your catalog, whether you run a hospital supply business, a distribution firm, or a new pharma venture.

Frequently Asked Questions

What is meropenem sulbactam 1.5 gm injection used for?

It treats serious bacterial infections in the lungs, urinary tract, abdomen, skin, and bloodstream, and it is used for meningitis and for fever in patients with low immunity. Hospitals rely on it when an infection needs a strong injectable antibiotic that stands up to common bacterial defenses.

What is the difference between meropenem and meropenem sulbactam?

Plain meropenem contains only the carbapenem antibiotic. The combination adds sulbactam, which blocks the enzymes some bacteria use to resist the drug and brings direct coverage against Acinetobacter, so it handles a wider range of resistant infections.

Why is sulbactam combined with meropenem?

Sulbactam protects meropenem from beta-lactamase enzymes and adds its own activity against Acinetobacter, a frequent cause of infections in intensive care. Together, they cover strains that meropenem alone can miss.

Is meropenem sulbactam injection available without a prescription?

No. It is a Schedule H prescription medicine and must be given by or under the supervision of a qualified doctor in a clinical setting.

How is meropenem sulbactam 1.5 gm injection given?

It comes as a dry powder that a healthcare professional mixes with sterile water for injection and delivers into a vein, usually as a slow infusion or injection set by the treating doctor.

Can I sell meropenem sulbactam injection under my own brand?

Yes. Torso Healthcare offers third-party manufacturing and PCD franchise options, so you can market it under your own brand name and packaging with full supporting documentation.

To source meropenem sulbactam 1.5 gm injection for your brand or franchise, contact Torso Healthcare for current pricing, pack options, and full product details.

The drug information on this page reflects standard prescribing references for meropenem and sulbactam.

Disclaimer: This page is meant for pharmaceutical businesses and healthcare professionals as reference information only. It is not medical advice. Meropenem sulbactam injection is a prescription medicine and should be used only under the guidance of a qualified doctor.